Prospective Functional, Gait, and Outcome Comparison Study of Medial Pivot

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Patients with degenerative joint disease can effectively be treated with a primary total knee replacement to reduce pain and improve function in their daily lives. Theoretically, achievement of normal knee motion using a medial pivot design in total knee replacements can be recreated in comparison to single radius designs, which could lead to an improvement in post-surgical outcomes and satisfaction with the procedure. The aim of this study is to compare two types of implant designs (medial pivot and single radius) in a total knee replacement using clinical outcomes, patient reported outcomes, and overall function assessed by a specialized gait laboratory.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: f
View:

• Subject is male or non-pregnant female aged between 18 and 75 years of age.

• Subject is willing to provide informed consent to participate in the research study.

• Subject is indicated for a primary total knee arthroplasty (TKA) based on the approved labeling of knee implant, either a medial pivot or single radius design, specifically: MicroPort Evolution Medial-Pivot Knee System, Cruciate Retaining (CS) or Stryker Triathlon Tritanium (CS)

• Subject does not have a history of previous prosthetic replacement device on the operative knee.

• Subject is currently ambulating and does not have a condition on the contralateral limb in the opinion of the investigator that would interfere with the gait laboratory evaluations.

• Subject is willing and able to comply with the schedule of events for the study and is available to return to the clinic for all required follow-up visits.

Locations
United States
Maryland
Sinai Hospital of Baltimore
RECRUITING
Baltimore
Contact Information
Primary
Martin Gesheff
mgesheff@lifebridgehealth.org
410-601-9467
Backup
Nirav Patel
nirpatel@lifebridgehealth.org
410-601-8860
Time Frame
Start Date: 2021-02-01
Estimated Completion Date: 2030-07-01
Participants
Target number of participants: 100
Treatments
Active_comparator: Medial-Pivot Knee System
Total Knee Arthroplasty will be done by implanting the MicroPort Medial Pivot Knee System into subjects.
Active_comparator: Single Radius Design Total Knee System
Total Knee Arthroplasty will be done by implanting the Stryker Triathlon Tritanium Knee System into subjects.
Sponsors
Leads: LifeBridge Health
Collaborators: MicroPort Orthopedics Inc., Rubin Institute for Advanced Orthopedics

This content was sourced from clinicaltrials.gov